In partnership with Sarcoma UK

We are delighted to have partnered with Sarcoma UK who have agreed to help us grow our community of sarcoma members. Growing this community will allow us to build a resource for reseachers which will make it easier for them to find participants for clinical trials and other research.

Sarcoma UK

There are over 600 live clinical trials for cancer in the UK at the moment. Let us help you find the right trial for you.

RareCan is the only organisation in the UK that specialises in finding clinical trials for patients with rare cancer.

Cancer clinical trial finder

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If you’d rather do things over the phone, click the button below and we’ll phone you at a time that’s convenient to you.

For a much more detailed guide, please have a look at our undifferentiated pleomorphic sarcoma information pack.

Undifferentiated pleomorphic sarcoma

Also known as:

  • UPS
  • Undifferentiated pleomorphic sarcoma not otherwise specified.
  • UPS- NOS

Older names no longer used:

  • malignant fibrous histiocytoma
  • MFH
  • malignant fibrohistiocytic tumours
  • malignant fibrous cytoma

What is UPS?

Undifferentiated pleomorphic sarcoma is often found as a painful, fast growing lump anywhere in the body, although they are more common in the legs. Under the microscope the cells appear undifferentiated, which means they don’t look like any normal mature cell. Pleomorphic means there will be a mixture of different forms of cell. These tumours are also genetically variable, so it is very hard to say what type of cell the cancer started in other than it came from the soft tissue.

A diagnosis of UPS is sometimes called a “diagnosis of exclusion” where it is used to label any soft tissue tumour that doesn’t fit any other description.

How rare is UPS?

Undifferentiated pleomorphic sarcoma is one of the more common sarcomas, although with only 1.2 cases per 100,000 each year in the UK, it is still very rare.

Who does UPS affect?

Although it can appear at any age, undifferentiated pleomorphic sarcoma tends to affect people between 50 and 70.

Why is RareCan interested in UPS?

RareCan is working to accelerate research into UPS by making it easier for researchers to connect with people who have it. You can help us do this by becoming a RareCan member and sharing information with us about your UPS cancer diagnosis. We will then get in touch with you about any research opportunities that might be suitable for you.

Looking for a different cancer type?

Please visit our ‘rare cancer list’ to search for your cancer type 

Useful links

If you are looking for further support with undifferentiated pleomorphic sarcoma we recommend the following websites:

Sarcoma UK

Sarcoma UK

Sarcoma UK is a charity for those with bone and soft tissue sarcoma diagnoses. They provide information on all types of sarcomas and have a patient support line to help assist with any queries and worries.

RareCan Member Stories:

How does our clinical trial service work?

1. Join RareCan

Create an account and answer a few simple questions about your diagnosis and treatment; view the trials that may be suitable for you

2. Get expert support

Our experienced team will work directly with you to screen you against the complex criteria for all open treatment trials. This takes 2-3 weeks.

3. Receive bespoke report

Our experienced team will work directly with you to screen you against the complex criteria for all open treatment trials. This takes 2-3 weeks.

4. Keep in touch

Keep us up to date with your treatment and we’ll keep you up to date with potentially suitable trials

Prefer to speak to someone?

If you’d rather do things over the phone, click the button below and we’ll phone you at a time that’s convenient to you.

How it works

How does our clinical trials service work?

Join RareCan

Create an account and answer a few simple questions about your diagnosis and treatment; view the trials that may be suitable for you

Get expert support

Our experienced team will work directly with you to screen you against the complex criteria for all open treatment trials. This takes 2-3 weeks.

Bespoke report

We’ll provide you with a report on trials we’ve considered, which may be suitable for you, and what actions you should consider taking.

Keep in touch

Keep us up to date with your treatment and we’ll keep you up to date with potentially suitable trials

Prefer to speak to someone?

If you’d rather do things over the phone, click the button below and we’ll phone you at a time that’s convenient to you.