Also Known As:

  • Myelofibrosis
  • MF
  • PMF
  • Overt Primary Myelofibrosis
  • Overt PMF

Why is RareCan interested in Myelofibrosis?

RareCan is working to accelerate research into Primary Myelofibrosis by making it easier for researchers to connect with people who have this rare form of blood cancer. You can help us do this by becoming a RareCan member and sharing information with us about your PMF diagnosis. We will then get in touch with you about any research opportunities that might be suitable for you.

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What is Primary Myelofibrosis?

Primary Myelofibrosis is a rare blood cancer that occurs in the bone marrow. It is often associated with mutations in the JAK2, CALR, or MPL gene markers, although around 10% of people with PMF do not carry any of these mutations. 

How rare is Myelofibrosis?

Myelofibrosis occurs in around 1 per 100,000 people per year.

Who does Myelofibrosis affect?

Primary Myelofibrosis mainly affects people over the age of 50 but it can happen at any age.  90% of people with PMF carry somatic mutations in the JAK2, CALR, or MPL gene markers, but 10% do not. 

Related Cancer Types

  • PMF is classified as a type of Myeloproliferative Neoplasm, a group of cancers that affect the bone marrow. 
  • Prefibrotic Primary Myelofibrosis
  • Polycythemia Vera
  • Essential Thrombocythaemia

Useful Links:

If you have Myelofibrosis/Primary Myelofibrosis/Overt Primary Myelofibrosis and are looking for support, we recommend the following websites:

Blood Cancer UK

Blood Cancer UK is a community dedicated to funding research and support for those affected by blood cancers like Myelofibrosis. 

MPN Voice is a charity for patients with Myeloproliferative Neoplasms and their families, carers and health professionals. 

Opportunities for Members with Primary Myelofibrosis

BioResource

The RareCan BioResource

Donating your samples for medical research

Joining RareCan gives you the ability to donate your tissue samples to the BioResource for medical research. Please note that signing up to RareCan does not commit you to donating tissue and you can cancel your membership at any time. If you have Myelofibrosis and would like to find out more, please click the button below.

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